Published: Tue, July 16, 2019
Sci-tech | By Jackie Newman

Four Lifestyle Choices May Offset Risk of Cognitive Decline

Four Lifestyle Choices May Offset Risk of Cognitive Decline

Individuals with excessive genetic danger and poor health habits had been about 3 times extra likely to develop dementia versus those with low genetic danger and good habits, researchers reported on Sunday. "Participants with high genetic risk and unfavorable lifestyle had a significantly higher risk of incident dementia compared with participants with low genetic risk and a favorable lifestyle". "In our study, adherence to a healthy lifestyle was associated with a reduced risk of dementia regardless of the genetic risk". Overall, it was found that genes alone made a three-fold difference in the likelihood someone will get dementia.

The team split the participants into five equal groups based on the combination of nearly 250,000 genetic variants associated with Alzheimer's disease in those of European ancestry. In the group with high genetic risk, 1.13% (95% CI, 1.01%-1.26%) with a favorable lifestyle developed dementia.

In order to assess genetic risk for dementia, the team looked at previous research to identify all currently-known genetic risk factors for Alzheimer's disease. Additionally, they had been grouped by lifestyle factors.

As Sano stated, there's no real downside to maintaining a healthy diet and exercise routine, going easy on alcohol, and refraining from smoking cigarettes.

Researchers considered no current smoking, regular physical activity, healthy diet and moderate alcohol consumption as "healthy".

The aim was to assess the genetic risks of developing dementia.

Upon analyses, investigators found that 61.8% of participants had a lifestyle categorized as favorable, 23.6% had an intermediate lifestyle, and 8.2% had unfavorable lifestyles.

AFCON 2019: Nigerian and Arsenal star Alex Iwobi exclusive interview
Nigeria booked their place in the semis after edging South Africa's Bafana Bafana, thanks to a late goal last Wednesday. We knew the goal would eventually come and had to be patient. "I am not bothered about emerging as the highest scorer".

A healthy lifestyle reduced dementia incidence in people with high-risk genetics, an analysis of almost 200,000 older adults in the UK Biobank showed.

She said: "Our findings are exciting as they show that we can take action to try to offset our genetic risk for dementia". The team grouped the participants into those with high, intermediate and low genetic risk for dementia.

It's easy to fall into the trap of believing dementia and Alzheimer's disease are the inevitable outcome of growing old, but a new study says that isn't the case.

In order to determine whether a healthy lifestyle was associated with a Lowe risk of dementia, without regard to genetic risk, investigators carried out a retrospective cohort study on patients from the UK Biobank study.

There are some limitations to the study. For example, the lifestyle data were collected at just one point in the study's duration. The population in the study was "overwhelmingly people with European ancestry: that's a problem with all our genetic studies that really has to be fixed", he said.

Hence, the researchers encourage further studies to strengthen the link of a healthy lifestyle and a reduced risk of dementia.

About 50 million folks have dementia, and Alzheimer's disease is the most common type. It is an irreversible, progressive, and incurable illness affecting the brain.

Like this: